Chaitali Anand, PhD

Postdoctoral Scholar
Radiology and Biomedical Imaging/ Physical Therapy and Rehabilitation Science
+1 734 834-6135

I joined the Chaumeil lab in October 2020 as a postdoc with a joint appointment in the Raj lab.  

I received my PhD in Translational Neuroscience from Wayne State University in Detroit, Michigan, in August 2020. My research focused on investigating age differences in hippocampal glutamate modulation in healthy humans while they performed an associative memory task, with proton magnetic resonance spectra being continuously acquired from unilateral hippocampi. The overarching goal of the study was to assess if glutamate modulation could be a potential biomarker of impending deficits in memory formation. I showed that, compared to the young, older adults demonstrate weak, to almost absent, modulation of hippocampal glutamate specifically during memory encoding, i.e. memory formation; and this was related to their poorer performance on the memory task. I was awarded an NRSA F31 predoctoral fellowship by the NIA (NIH) to conduct this work.

My research interest lies in exploring normal and pathological age-related changes in neuro-energetics and neurometabolism. I am also interested in learning and applying computational approaches to model neurodegenerative disease progression. Outside of lab, I am interested in running while listening to podcasts, hiking, photography, painting, and playing badminton.

Publications: 

Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome.

bioRxiv : the preprint server for biology

Anand C, Torok J, Abdelnour F, Maia PD, Raj A

Cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease.

bioRxiv : the preprint server for biology

Torok J, Maia PD, Anand C, Raj A

Connectome-based biophysics models of Alzheimer's disease diagnosis and prognosis.

Translational research : the journal of laboratory and clinical medicine

Torok J, Anand C, Verma P, Raj A

Test-retest and repositioning effects of white matter microstructure measurements in selected white matter tracts.

Neuroimage. Reports

Anand C, Brandmaier AM, Lynn J, Arshad M, Stanley JA, Raz N

Microstructure of Human Corpus Callosum across the Lifespan: Regional Variations in Axon Caliber, Density, and Myelin Content.

Cerebral cortex (New York, N.Y. : 1991)

Lynn JD, Anand C, Arshad M, Homayouni R, Rosenberg DR, Ofen N, Raz N, Stanley JA

White-matter microstructural properties of the corpus callosum: test-retest and repositioning effects in two parcellation schemes.

Brain structure & function

Anand C, Brandmaier AM, Arshad M, Lynn J, Stanley JA, Raz N

Working Memory Modulates Glutamate Levels in the Dorsolateral Prefrontal Cortex during 1H fMRS.

Frontiers in psychiatry

Woodcock EA, Anand C, Khatib D, Diwadkar VA, Stanley JA