Brice Tiret, PhD

Post-doctoral Scholar
Physical Therapy and Rehabilitation Science

I am a post-doctoral scholar in the Physical Therapy and Rehabilitation Science Department at UCSF since January 2017.

My current research involves methodological development of biomarkers of neuro-inflammation using Magnetic Resonance Spectroscopy (MRS). I specialize in in vivo proton and phosphorus single voxel MRS, as well as hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging (HP 13C MRSI) methods.

I received my PhD from the Université Paris-Saclay in France. As a PhD student, I was looking at methodological development for X nuclei NMR spectroscopy with in vivo neurological applications in rodents. Looking at different models of Huntington’s disease, I was interested at pH variations as a biomarker, as well as metabolomics changes measured using dynamic 31P and 13C MRS.


Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits.

International journal of molecular sciences

Krukowski K, Chou A, Feng X, Tiret B, Paladini MS, Riparip LK, Chaumeil MM, Lemere C, Rosi S

Using 31P-MRI of hydroxyapatite for bone attenuation correction in PET-MRI: proof of concept in the rodent brain.

EJNMMI physics

Lebon V, Jan S, Fontyn Y, Tiret B, Pottier G, Jaumain E, Valette J

Experimental strategies for in vivo13C NMR spectroscopy.

Analytical biochemistry

Valette J, Tiret B, Boumezbeur F

Evidence for a "metabolically inactive" inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Tiret B, Brouillet E, Valette J

Negative childhood experiences alter a prefrontal-insular-motor cortical network in healthy adults: A preliminary multimodal rsfMRI-fMRI-MRS-dMRI study.

Human brain mapping

Duncan NW, Hayes DJ, Wiebking C, Tiret B, Pietruska K, Chen DQ, Rainville P, Marjanska M, Ayad O, Doyon J, Hodaie M, Northoff G

Fast and accurate semi-automated segmentation method of spinal cord MR images at 3T applied to the construction of a cervical spinal cord template.

PloS one

El Mendili MM, Chen R, Tiret B, Villard N, Trunet S, Pélégrini-Issac M, Lehéricy S, Pradat PF, Benali H

Validation of a semiautomated spinal cord segmentation method.

Journal of magnetic resonance imaging : JMRI

El Mendili MM, Chen R, Tiret B, Pélégrini-Issac M, Cohen-Adad J, Lehéricy S, Pradat PF, Benali H

GABA in the insula - a predictor of the neural response to interoceptive awareness.


Wiebking C, Duncan NW, Tiret B, Hayes DJ, Marja?ska M, Doyon J, Bajbouj M, Northoff G

Glutamate concentration in the medial prefrontal cortex predicts resting-state cortical-subcortical functional connectivity in humans.

PloS one

Duncan NW, Wiebking C, Tiret B, Marjanska M, Marjanska M, Hayes DJ, Lyttleton O, Doyon J, Northoff G